USEARCH manual Home Software Services About Contact 12-Jun-2018 New paper shows that one in five taxonomy annotations in SILVA and Greengenes are wrong. 18-Apr-2018 New paper shows that taxonomy prediction accuracy is <50% for V4 sequences. 05-Oct-2017 PeerJ paper shows low accuracy of closed- and open-ref. QIIME OTUs. 22-Sep-2017 New paper shows 97% threshold is wrong, OTUs should be 99% full-length 16S, 100% for V4. 24-Nov-2016 UPARSE tutorial video posted on YouTube. Make OTUs from MiSeq reads. USEARCH Download 32-bit Buy 64-bit New in v11 Tech support Documentation Commands Topics OTU analysis Sequence search Sequence clustering Taxonomy Diversity Octave plots Machine learning Chimeras Read quality Paired reads Publications Obsolete page.